Oral semaglutide missed its primary endpoint for drinking. The VA’s new 622-person phase 3 is built on the one result that trial failed to get.
Finding purpose in retirement is the part no one plans for. Why a project beats a blank calendar, what the research on hobbies and mattering shows, and how to start before you retire.
Updated September 26, 2026 with a note that Lilly is testing brenipatide as a weekly shot, not a monthly one. Updated September 9, 2026: added a section below on the smoking-relapse-prevention trial and a newly registered COPD trial. I quit drinking after getting headaches, looking at the evidence and deciding it wasn’t worth it. Most
Here’s a question: when’s the last time you had a real conversation with a friend? Not the “how about those Cowboys” bullshit at your kid’s game or the polite catch-up at some work thing. An actual conversation where you talked about what’s really going on. If you’re drawing a blank, you’re not alone. Which is
