Retatrutide isn’t FDA approved, but it has a street name, a grey market with customer service, and Wall Street’s full attention. What the strongest weight-loss drug ever tested means, and why I’m not taking it.
A new study found people on GLP-1 drugs took fewer steps after starting. I lost the weight and moving got easier, so I went looking for why most people slow down.
I’m on Zepbound at a normal dose, the kind a doctor prescribes and a pharmacy fills. A reader sent me a video this week that’s a good way into a question I keep getting asked. In it, the New Zealand GP Brad Stanfield, who runs an evidence-minded health channel, explains that he injects 1.25 milligrams
The CVS Caremark deal just moved a trillion-dollar stock. Here is how Americans actually get Zepbound and Mounjaro across the five channels, who really decides, and what each one costs in 2026.
People on tirzepatide ask if brenipatide is the upgrade. People reading about brenipatide ask how it compares to the drug everyone is already on. Same class. Very different jobs. A head-to-head comparison.
Lilly’s retatrutide just delivered bariatric-equivalent weight loss in Phase 3. The numbers, why the low dose is the real story, and the gray-market reality that got there first.
I am at goal weight on Zepbound. SURMOUNT-MAINTAIN is the trial I have been waiting for. Here is what holding the line at a lower dose actually looks like.
After years of not getting a physical (out of laziness and the fear “they will just tell me to lose weight and eat broccoli”), I finally got a physical last October. I knew I had gained a lot of weight but seeing “373lbs” on the scale gave me a profound shock. I had fastidiously avoided
