A million-person Lancet study shows older adults with obesity now match normal-weight peers on blood pressure and cholesterol, thanks to cheap statins and blood-pressure pills, not weight loss.
The “five times the risk” number is real. The useful lesson for a fifty-year-old is smaller, less sexy, and more actionable. I have read the claim that VO2 max is the single best predictor of how long you will live so many times that I had stopped seeing it. It is everywhere in the longevity
Equinox sells a $40,000 longevity membership with a thousand people waiting. I run the same core protocol out of my garage for a few thousand a year. Here’s where the other $39,000 actually goes, and why some of the most expensive testing can leave you worse off.
A new ingredient just cleared the FDA, the first in twenty years. It sent me looking at what sunscreen actually does, where the fear is overblown, and whether a fair-skinned guy in Boston needs to think about it more than a couple of times in the summer. I am about as fair as a person
I lift, track my labs, and read the studies. I still ended up with a cabinet full of maybes, while my wife just buys the one gummy she likes at Target. So I stopped asking which ones work and started asking who got paid when I bought them. I cleaned out my medicine cabinet last
The most influential cholesterol educator alive can’t tolerate statins or ezetimibe. When he needed the expensive PCSK9 drug, his insurer said his numbers were too good to cover.
A research platform lets anyone turn health records into a publishable-looking study in an afternoon. Here is how that floods the GLP-1 and cancer literature, and how I read these studies now.
Most “AI predicts disease” papers don’t survive a second read. This one does, and it points at a kind of heart risk your echo was never built to see. I’ve spent my whole career in machine learning, so I read the steady drip of “AI predicts your death” headlines the way a mechanic reads ads
I take two drugs that would get an Olympian banned: testosterone and a GLP-1. I will never compete, so the only thing they enhance is my ability to climb stairs and lift a barbell after 50. Here is what they actually do, and what they don’t.
My friend is sober, goes to AA, and just started the Wegovy pill for the cravings that never left. Here is what ninety years of alcohol treatment, from the Twelve Steps to a GLP-1, actually shows.
