My Zepbound Will Go Generic. Lilly Is in Court to Make Sure Retatrutide Doesn’t.
The fight that decides what you will pay for the strongest obesity drug yet seen in large trials comes down to a single amino acid, and nobody has won it yet.
GLP-1
Healthcare, Preventive Health
Peptides Promise Everything. An FDA Panel Just Said Yes to Six of Seven.
The FDA’s compounding committee voted on seven peptides, recommending BPC-157. What peptides are, why the market exploded, and what the vote does and does not decide.
Medicine 3.0, Preventive Health
Daily Low-Dose Tadalafil: What’s Proven, What’s Plausible, and What Isn’t
My TRT clinic prescribed 5 mg of tadalafil a day. Here is what it is actually proven to do for the prostate and ED, what the podcasts oversell, and the one drug interaction to never ignore.
Medicine 3.0, Testosterone/TRT
I Take Testosterone. One Low Number Shouldn’t Put You on It.
A single low testosterone reading isn’t a diagnosis. I’m on TRT, and here’s how low testosterone is actually diagnosed, what TRT does, and the fertility risk young men miss.
GLP-1, Medicine 3.0, Preventive Health
Why I Take a Diabetes Drug and Have Never Had Diabetes
I take a diabetes drug and have never had diabetes. A plain-English map of the type 2 diabetes drugs, and why the best ones now protect your heart and kidneys, not just blood sugar.
Cholesterol, Heart & Bloodwork, Medicine 3.0
The First PCSK9 Cholesterol Pill Was Just Approved. Here’s Who Might Need It
The FDA approved Lipfendra (enlicitide), the first oral PCSK9 inhibitor. What it costs, how the pill compares to the shots, and who actually needs it.
Nutrition, Preventive Health
Romaine Keeps Making People Sick. I Quit It, and I’m Not Missing Much.
A cyclospora outbreak just sickened 1,645 people across 34 states, and romaine keeps causing E. coli recalls. Is romaine lettuce safe to eat, and is it even worth it? A hard look, and what I eat instead.
Longevity, Mental health, Preventive Health, Work
Don’t Retire From Something. Build Toward Something.
Finding purpose in retirement is the part no one plans for. Why a project beats a blank calendar, what the research on hobbies and mattering shows, and how to start before you retire.
GLP-1
Tirzepatide Wins Weight Loss. Semaglutide Has the Hard-Outcome Data.
A BMJ analysis of 262 trials crowned tirzepatide the weight-loss king. But the drug with the hard survival and heart-attack data is the one that finished fifth.
Heart & Bloodwork, Preventive Health
The 2025 Blood Pressure Guidelines Didn’t Change Who Has Hypertension. They Replaced an Outdated Calculator.
The 2025 blood pressure guidelines sound like a shake-up. Here’s what actually changed about who gets medication, and why it barely moved the needle.